Yeah, the resistors are 0-ohm.
Have you attempted to move the USB resistors to the RPi slots yet?
If you’re still having issues, you can try moving the SW UART to the HW UART or switching the 5V to the 3.3V I/O.
The IO0 line indicates there is a pending IRQ flag that needs to be tended to, the fact that this light is coming off can either indicate that the IRQ Flag was serviced (with the clear IRQ command) – or that the module lost power and reset.
You can find a list of possible IRQ Flags in this documentation as well as in the source code of the python library.